Case
#44 "Send Her Home When Her Husband
Gets Here" by Charlene Babcock Irvin, MD
During sign out rounds, you walk by a 25 y/o
female, resting on the cot with her eyes
shut. The leaving attending notes that she
received Prochlorperazine (Compazine) and
Diphenhydramine (Benedryl) for a headache,
was feeling better, and her husband was on
his way to pick her up. He then notes that
she is a return visit and was here yesterday
for headache and also got Compazine and
Benedryl then with a good result.
Approximately 15 minutes later, you note the
husband at the bedside and approach the
headache patient for a re-evaluation.
She is a thin African American, lying
still with her eyes shut and the head of the
bed up at 45 degrees. She speaks clearly,
but slowly.
You read from the history already
documented that she has a history of
headaches, and has been having headaches
intermittently for the past three days. She
has taken Ibuprofen at times, which seems to
help. She came yesterday, and after the meds
felt much better, but today the headache
came back. On a scale of 1-10, when she came
in, the headache pain was graded at 10. Now
she feels much better and the pain is only
2. The pain is not throbbing, but constant,
and not localized to any particular part of
the head.
You try to ask the usual CLORIDE (Chronicity,
Location, Onset, Radiation, Intensity,
Duration, and Exacerbating/alleviating
factors) questions about the pain but
history is difficult as she is very slow to
answer. Her speech is clear and it doesn’t
seem like the usual reaction to drowsiness
from Compazine.
You do find out (with the husband's help)
that these headaches the past three days are
different from her previous headaches
because they are more severe in intensity of
pain, and are recurrent. Usually she gets
tension headaches, which get better with
Ibuprofen. Initially the ibuprofen seemed to
help, but yesterday’s and today’s headaches
were the worst headaches she has ever had
and didn’t get better with ibuprofen. The
pain is generalized all over her head, and
the onset is very sudden. There is no
radiation. The pain is very intense at
first, but seems to get better with the
medication we gave her. The headache
yesterday lasted a few hours, and today it
has been a few hours. She’s not sure what
brings the headache on, but lying down with
her head elevated seems to help.
ROS: She denies fever, photophobia, neck
pain, or trauma. She denies any visual
changes, toothaches, sinus drainage, ear
pain, chest pain, shortness of breath,
abdominal complaints, rashes, or weakness.
FH: There is a family history of migraines.
SH: No drug or alcohol abuse
Admission vital signs (from three hours
earlier): BP=128/70, HR=88, RR=18, Afebrile,
Sat=96% on room air
PE:
HEENT: Pupils mid position, reactive, and
she has no papilladema. Neck is supple,
teeth are in good repair without tenderness.
No sinus tenderness. Throat normal.
Heart: RRR and normal
Lungs: Clear and normal
ABD: Soft and normal
Ext: No rashes or lesions
Neurologic: Cranial nerves normal
Motor 5/5 throughout
Sensory intact
Reflex’s normal
Cerebellar (finger to nose) normal.
Mental status: She is very slow in answering
questions, but she has no slurred speech.
She is not alert (preferring to lay with her
eyes closed, and taking time to answer), but
oriented x3 (it takes her 15 seconds to tell
you the month, and another 15 seconds to
tell you what is the date—but she gets both
correct). Her GCS =14.
Because of the unusual nature of the
headache (severe, intermittent, with a
positional component) and because she notes
that they are the ‘worst’ headaches and
sudden in onset, you decide to add on a CT
with the understanding you will be doing an
LP if the CT is negative. While it is not
typical for headaches from a subarachnoid
hemorrhage to be intermittent, the sudden
onset and description of ‘worst’ headache
are worrisome enough red flags for you to
pursue further workup, especially as you
think her slowness cannot be entirely
explained by the medications. Many refer to
this type of a headache as a thunder clap
headache (TCH). You also order some baseline
labs and an acucheck.
About 20 minutes later, as you are walking
by the patient’s room, as the nurse calls
out for some help. When you go in, you see
the nurse doing a sternal rub without
response. The nurse tells you the patient is
not breathing but has a pulse.
You grab the ambu bag on the wall, put the
HOB down flat, and begin to assist
respirations as you move the patient to the
resuscitation area.
When you ask what happened, the nurse notes
she was in the room doing the acucheck when
she noticed the patient had stopped
breathing. She seemed like she was sleeping,
but when she didn’t respond, she realized
she was not conscious or breathing.
As you get to the resuscitation area and
ready intubation equipment, the patient
begins to spontaneously breath and over the
next 3-4 minutes starts waking up. VS on
arrival to resuscitation room were: BP
155/85, RR=0, P=70
1. What CNS structures maintain
consciousness?
2. What could have happened?
3. What do you order?
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