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  Case#5 11/26/07 The bleeding Brain on Warfarin

A 58 y/o female on warfarin for atrial fibrillation presents after tripping and hitting her head into the kitchen cabinet. She complains of a headache. Neurological exam is non-focal, vital signs are normal, but her headache is severe. You order a CT scan, and consider reversal of anticoagulation.

1. How long does vitamin K take to work? What is the difference between oral, subcutaneous and IV?

2. Should you order FFP or Cryoprecipitate? 3. What are the other options to reverse this coagulopathy?

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